ifornians of Asian Ancestry, 1988 to 2007

nloaded kground: Hepatocellular carcinoma (HCC) represents a significant health disparity affecting Asian icans, a population comprised of distinct ethnic groups. The purpose of this article is to analyze rnians of Asian ancestry with HCC with respect to socioeconomic status, demographic factors, stage ase, treatment received, and survival. thods: To investigate ethnic differences in survival, we analyzed ethnically disaggregated data from Californians of Asian ancestry with HCC diagnosed in 1988 to 2007 and reported to the California r Registry. ults: Compared with the average of all ethnic groups, cause-specific mortality was significantly higher Laotian/Hmong [hazard ratio, 2.08; 95% confidence interval (95% CI), 1.78-2.44] and Cambodian ts (hazard ratio, 1.26; 95% CI, 1.06-1.51), groups with higher proportions of their populations at low of socioeconomic status; in addition, Laotian/Hmong patients disproportionately presented at later of disease, with only 3% receiving local surgical treatment, resection, or liver transplantation. After ment for time of diagnosis, age at diagnosis, gender, geographic region, stage at diagnosis, type of surnd socioeconomic status, survival disparities remained for both groups (Laotian/Hmong hazard ratio, 5% CI, 1.28-1.79; Cambodian hazard ratio, 1.24; 95% CI, 1.03-1.48). clusions: Our hypothesis that survival outcomes would differ by ethnicity was verified. act: Research is needed not only to develop more effective treatments for HCC but also to develop unity-based interventions to recruit Asian Americans, particularly Laotian/Hmong and Cambodians, comm for hepatitis B screening and into medical management to prevent or detect this tumor at an early stage. Cancer Epidemiol Biomarkers Prev; 19(11); 2747–57. ©2010 AACR.